Prophylactic Effect of Dexamethasone on Regorafenib-Related Fatigue and/or Malaise: A Randomized, Placebo-Controlled, Double-Blind Clinical Study in Patients with Unresectable Metastatic Colorectal Cancer (KSCC1402/HGCSG1402)

Hiroaki Tanioka,Yuji Miyamoto,Akihito Tsuji,Masako Asayama,Takeshi Shiraishi,Satoshi Yuki,Masahito Kotaka,Akitaka Makiyama,Mototsugu Shimokawa,Takayuki Shimose,Satohiro Masuda,Takuhiro Yamaguchi,Yoshito Komatsu,Hiroshi Saeki,Yasunori Emi,Hideo Baba,Eiji Oki,Yoshihiko Maehara

Prophylactic Effect of Dexamethasone on Regorafenib-Related Fatigue and/or Malaise: A Randomized, Placebo-Controlled, Double-Blind Clinical Study in Patients with Unresectable Metastatic Colorectal Cancer (KSCC1402/HGCSG1402)

2018

Hiroaki Tanioka
Yuji Miyamoto
Akihito Tsuji
Masako Asayama
Takeshi Shiraishi
Satoshi Yuki
Masahito Kotaka
Akitaka Makiyama
Mototsugu Shimokawa
Takayuki Shimose
Satohiro Masuda
Takuhiro Yamaguchi
Yoshito Komatsu
Hiroshi Saeki
Yasunori Emi
Hideo Baba
Eiji Oki
Yoshihiko Maehara

Background: Regorafenibis an oral multikinase inhibitor with a provensurvival benefit for metastatic colorectal cancer patients. The KSCC1402/HGCSG1402 study in

Keywords:

Pathology
Dexamethasone
Medicine
Placebo
Regorafenib
Malaise
Colorectal cancer
Internal medicine
Immunology
Clinical endpoint
Gastroenterology
Common Terminology Criteria for Adverse Events
Chemotherapy

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