045 - Predictive factors of ST-segment resolution after primary angioplasty and clinical outcome

2010
In the setting of acute myocardial infarction (AMI), early resolution of ST-segmentelevation was a useful predictor of final infarct size, left ventricular function and clinical outcome. Aim to determine the predictive factors of ST-segmentresolution immediately following primary coronary angioplasty for AMI. Methods primary angioplasty was performed in 270 consecutive patients with first AMI, they were divided into 2 groups according to whether ST-segmentresolution occurred 1 hour after the procedure. ST-segmentresolution ≥ 70% was considered as ‘complete’ ST-segmentresolution, whereas ST-segmentresolution Results of the 270 patients, 156 (57.8%) had complete ST-segmentresolution. Patients with pre-infarction anginahad a greater degree of ST-segmentresolution than those without angina(71 ±21% vs. 49± 43%, p On multivariate analysis, the absence of pre-infarction angina(OR=2.7; CI 1.7-3.4, p=0.03) as well as the admission after H4 (OR=3.5; CI 1.58-8.06, p=0.002), patient age ≥ 70 year(OR= 5.6; CI 2.23-14.4, p There was a significant difference in survival free of major adverse cardiovascular events, at multivariate analysis=, incomplete ST-segmentresolution was an independent factor of 1-year mortality (p=0.016). Conclusions Rapid ST-segmentresolution was associated with a better clinical outcome and prognosis after successful primary PTCA. Pre-infarction angina, age
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