Regional distribution of layer-specific circumferential residual deformations and opening angles in the porcine aorta
2019
Abstract Information on the layer-specific residual deformations of aortic tissue and how these vary throughout the vessel is important for understanding the regionally-varying aortic functions and pathophysiology, but not so much can be found in the literature. Toward this end, porcine
aortaswere sectioned into eighteen rings, with one ring from each anatomical position radially cut to obtain the zero-stress state for the intact wall and the other ring dissected into intimal-medial and
adventitiallayers; these rings were then radially cut to reach the zero-stress state for the intima-media and
adventitia. Peripheral variations in internal/external circumferences, thickness, and opening angle of the intact wall and its layers were measured through image analysis at the no-load and zero-stress states. Intact wall and layer circumferences at both states significantly declined along the
aorta, as did intact wall and intimal-medial but not
adventitialthickness.
Adventitiaexhibited the greatest opening angles, approaching 180 deg all over the
aorta. The opening angles of the intima-media and intact wall were quite similar, with the highest values in the
ascending aorta, the lowest at the diaphragm, and increasing subsequently. Bending-related residual stretches were released by radial cutting that were compressive internally and tensile externally, displaying distinct axial variation for the intima-media and intact wall, and non-significant variation for the
adventitia. Evidence is provided for the release upon layer separation of compressive stretches in the intima-media and of tensile stretches in the
adventitia, whose values were smallest in the descending
thoracic aortaand highest near the iliac artery bifurcation.
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