The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
2017
The
N6-methyladenosine(m6A) modification in mRNAs, generated by the enzyme METTL3, controls normal human hematopoietic stem/
progenitor celldifferentiation and maintains the undifferentiated leukemic phenotype of human acute
myeloid leukemiacells.
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