Letter re: Evaluation of hyperacute infarct volume using ASPECTS and brain CT perfusion core volume

Demeestere et al.1 compared hyperacute infarct volume using the Alberta Stroke Program Early CT Score (ASPECTS) and brain CT perfusion and found no significant difference. ASPECTS and CT perfusion-based studies have already established their critical role in selecting patients for thrombolysis and mechanical recanalization.2,3 In this study, ASPECTS or CT perfusion core volume was compared with MRI diffusion-weighted imaging (DWI) lesion volume.1 However, MRI was performed within 100 minutes (median 60 minutes) of CT perfusion and 49% of patients received thrombolysis before MRI.