Patient manifested as left ventricular non-compaction.

A woman in her 20s suffering from chest tightness was referred with suspected cardiomyopathy by echocardiogram. No skeletal muscle and mental abnormalities were found. Her mother died of advanced heart failure at the age of 48, but the exact cause of heart failure is unclear. Cardiac magnetic resonance demonstrated normal left ventricular (LV) wall thickness; LV cavity was mildly enlarged (figure 1A); LV ejection fraction (EF) was decreased (EF=44.5%). We found prominent hypertrabeculations at mid-apical portions of the left ventricle (the ratio of the non-compacted to compacted myocardial layers=3.3, figure 1B). Furthermore, patchy non-ischaemic …