Immediate and long-term effect of mitral balloon valvotomy on left ventricular volume and systolic function in severe mitral stenosis

Abstract To determine the immediate and long-term effect of mitral balloon valvotomy (MBV) on left ventricular (LV) volume and function, we studied 17 patients (mean age 27 ± 9 years) with severe mitral stenosis undergoing MBV by cardiac catheterization and angiography before and immediately after MBV and at mean 12 months later. At baseline, LV end-diastolic volume index (EDVI) was reduced. Ten patients had EDVI ≤55 ml/m 2 , and four patients (23.5%) had LV ejection fraction 2 to 66 ± 17 ml/m 2 ( p 2 ( p 2 to 41 ± 12 ml/m 2 ( p 2 ( p p p p p p −5 to 1280 ± 231 dyne/sec/cm −5 ( p