A case of pheochromocytoma crisis with persistent hypotension successfully managed with vasopressin

Abstract We report the first case of pheochromocytoma crisis with hypotension that was successfully treated with vasopressin. A 64-year-old patient was diagnosed as pheochromocytoma crisis. Although irregularities in circulating plasma volume were corrected by fluid management, hypotension due to vasodilation persisted. Since it was considered to be desirable to use a vasoconstrictor whose action was not mediated via adrenergic receptors, we administrated vasopressin as a non-adrenergic vasopressor. Consequently, sufficient vasoconstriction and pressor effect were achieved without any complications. Finally, the adrenalectomy was performed safely. Vasopressin might be effective and safe treatment for pheochromocytoma crisis with hypotension caused by vasodilation.