Clinical Relevance of Bronchial Anthracofibrosis in Patients with Chronic Obstructive Pulmonary Disease Exacerbation
2014
Background: Bronchial anthracofibrosis (BAF), which is associated with exposure to biomass smoke in inefficiently ventilated indoor areas, can take the form of
obstructive lung disease. Patients with BAF can mimic or present with an
exacerbationof chronic obstructive pulmonary disease (COPD). The purpose of the current study was to investigate the prevalence of BAF in Korean patients with
COPD exacerbationas well as to examine the clinical features of these patients in order to determine its clinical relevance. Methods: A total of 206 patients with
COPD exacerbationwere divided into BAF and non-BAF groups, according to computed tomography findings. We compared both clinical and radiologic variables between the two groups. Results: Patients with BAF (51 [25%]) were older, with a preponderance of nonsmoking women; moreover, they showed a more frequent association with exposure to wood smoke compared to those without BAF. However, no differences in the
severityof
illnessand clinical course between the two groups were observed. Patients in the BAF group had less severe airflow obstruction, but more common and severe
pulmonary hypertensionsigns than those in the non-BAF group. Conclusion: Compared with non-BAF COPD, BAF may be associated with milder airflow limitation and more frequent signs of
pulmonary hypertensionwith a more severe grade in patients presenting with
COPD exacerbation.
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