4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions
2013
On the purpose of looking for better
cholesterol absorption inhibitors, several
trifluoromethylsubstituted
ezetimibeanalogs 1a-d were designed and synthesized. The key steps in the synthesis of these optically pure trans-4-CF3-
beta-lactamsinclude chira
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