Unexplained infertility: overall ongoing pregnancy rate and mode of conception
2011
results: Of all couples 81.5% (356/437) achieved an ongoing
pregnancyand 73.9% (
263/356) of the
pregnancieswere conceived spontaneously. There were 408 couples (93.4%) in strategy-1, 21 (5.0%) in strategy-2 and 8 (1.8%) in strategy-3. In total, 33 (7.6%) couples entered the wrong strategy. There were 104 couples (23.8%) who discontinued fertility treatment prematurely: 26 on doctor’s advice (with 4 still becoming pregnant) and 78 on their own initiative (with 33 still achieving a
pregnancy). Predictors for overall
pregnancychance and mode of conception were duration of infertility, female age and obstetrical history. conclusions: Overall success rate in couples with
unexplained infertilityis high. Most
pregnanciesare conceived spontaneously. We recommend that if the
pregnancyprognosis is good, expectant management should be suggested. The prognosis criteria for treatment with IUI or IVF needs to be investigated in randomized controlled trials.
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