Propafenon aşırı dozuna bağlı gelişen kardiyak arrest

Propafenoneis a group 1C antiarrhythmic agent. Serious side effects such as cardiac arrest may occur when excessive intake. A sixteen year-old female was admitted to emergency department with nausea, vomiting, and altered mental status. Wide QRS tachycardia and subsequent ventricular fibrillationoccurred following gastric lavagein the patient who confessesthat she had taken excessive amount (4500mg propafenone) of drug for the purpose of suicide. After cardiopulmonary resuscitationfor ten minutes the patient was intubated because of blurred consciousness and shallow breathing. Transtoracic echocardiography didn’t show any pathology. First degree AV blockand widened QRS complexesdetermined in her electrocardiograph (ECG) after resuscitation. These pathological changes in the ECG and clinical status of the patient improved completely in the following days and she was discharged from hospital without any sequelae. OZET