Sexual and Endocrine Function in Uraemia

The kidney has long been recognized as a key organ in relation to endocrine function, both as a target site for hormones and as a major site of hormone metabolism. More recently the kidney has been found to possess a number of unique endocrine and paracrine activities in its own right. It is, therefore, no surprise that renal failure should be associated with such a wide variety of endocrine dysfunctions.