Test–retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943

Aybala Saricicek,Jason I. Chen,Beata Planeta,Barbara Ruf,Kalyani Subramanyam,Kathleen Maloney,David Matuskey,David Labaree,Lorenz Deserno,Alexander Neumeister,John H. Krystal,Jean-Dominique Gallezot,Yiyun Huang,Richard E. Carson,Zubin Bhagwagar

Test–retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943

2015

Aybala Saricicek
Jason I. Chen
Beata Planeta
Barbara Ruf
Kalyani Subramanyam
Kathleen Maloney
David Matuskey
David Labaree
Lorenz Deserno
Alexander Neumeister
John H. Krystal
Jean-Dominique Gallezot
Yiyun Huang
Richard E. Carson
Zubin Bhagwagar

Purpose [11C]P943 is a novel, highly selective 5-HT1B PET radioligand. The aim of this study was to determine the test–retest reliability of [11C]P943 using two different modeling methods and to perform a power analysis with each quantification technique.

Keywords:

Medicine
Radioligand
Nuclear medicine
light nucleus
modelling methods
highly selective
graphical analysis

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