Besides the Genome, the Environmentome?

The occurrence of disease in humans, their response to treatment, and all their medical history are determined by the products of their genes (gene sequence and gene expression) and of their environmental encounters that do not act independently of each other. Developmental plasticity, epigenetics, and stochasticity govern interactions between environmental factors and gene expression and in so doing make each human phenotype unique. Although considerable (and successful) effort has been made to use all available bioinformatic resources to study the human genome and its individual diversity, the environment has not been subject to the same passion of data scientists.