Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines

Background Meningiomatumors arise in arachnoidmembranes, and are the most reported central nervous system(CNS) tumors worldwide. Up to 20% of grade I meningiomatumors reoccur and currently predictive cancer stem cells(CSCs) markers for aggressive and drug resistant meningiomasare scarce.