PP-091 INVESTIGATING THE POTENTIAL EFFECTS OF SUNITINIB IN K-562 CHRONIC MYELOGENOUS LEUKEMIA CELL LINE AND ASSESSMENT OF GENE PROFILING

Introduction: The bone marrow in addition to being the origin of primary hematological malignancies is also commonly involved by metastatic solid tumors. The malignancies of prostate, breast, lungs, kidney, thyroid and gastric in adults are the primary tumors, which frequently involve bone marrow. Leukoerythroblastosis (LEB) and unexplained cytopenias are strong indicators of the necessity of bone marrow examination. Case report: A 45-year-old woman was referred from family physicians to our clinic because of cytopenia. Organomegaly and palpable lymphadenopathy was not detected at physical examination. The peripheral blood cell count parameters included anemia, leukocytosis, thrombocytopenia and