Protection from Hendra virus infection with Canarypox recombinant vaccine
2016
French researchers have found a new potential vaccine against the rare, often-deadly Hendra virus that spreads from horses to humans. A team led by Branka Horvat at the International Center for Infectiology Research in the collaboration with Merial, developed new vaccine by combining a safe version of the
Canarypox viruswith Hendra virus (HeV) proteins that promote an immune response in the host. The researchers vaccinated hamsters and then administered a
lethal doseof virus. The vaccine provided immunity from HeV by stimulating the production of
neutralizing antibodies, inhibiting
viral sheddingand protecting animals from clinical disease. The immunogenicity of this vaccine was then confirmed in horses. The study puts forward a potential new route to stop the spread of HeV and protect communities that come into contact with horses, thereby protecting both animal and human health.
Keywords:
-
Correction
-
Source
-
Cite
-
Save
40
References
9
Citations
NaN
KQI