Minichromosome maintenance complex component 8 and 9 gene expression in the menstrual cycle and unexplained primary ovarian insufficiency

Purpose DNA repairgenes Minichromosome maintenancecomplex component (MCM) 8 and 9 have been linked with gonadal development, primary ovarian insufficiency(POI), and age at menopause. Our objective was to characterize MCM 8 and 9 gene expression in the menstrual cycle, and to compare MCM 8/9 expression in POI vs normo-ovulatory women.