Maximizing the Impact of Physiologically-Based Oral Absorption Modeling and Simulation.
2017
Abstract The challenge of bringing innovative medicines to patients in combination with intense competition within the
pharmaceutical industryhas induced companies to develop quality medicines more efficiently and cost-effectively. State-of-the-art approaches to advance
drug developmenthave never been so urgent. One such approach that has been gaining traction within the industry is the application of
modelingand
simulation. In this commentary, the benefits of physiologically based oral absorption
modelingand
simulationin
drug developmentare highlighted and suggestions for maximizing its impact are provided.
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