Molecular subtyping of European swine influenza viruses and scaling to high-throughput analysis

Background Swine influenza is a respiratory infection of pigs that may have a significant economic impact in affected herds and pose a threat to the human population since swine influenza A viruses (swIAVs) are zoonotic pathogens. Due to the increasing genetic diversity of swIAVs and because novel reassortantsor variants may become enzooticor have zoonotic implications, surveillance is strongly encouraged. Therefore, diagnostic testsand advanced technologies able to identify the circulating strains rapidly are critically important.