A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors.

Paul J. Wood,Robyn Strong,Grant A. McArthur,Michael Michael,Elizabeth Algar,Andrea Muscat,Lin Rigby,Melissa J Ferguson,David M. Ashley

A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors.

2018

Paul J. Wood
Robyn Strong
Grant A. McArthur
Michael Michael
Elizabeth Algar
Andrea Muscat
Lin Rigby
Melissa J Ferguson
David M. Ashley

Purpose This was an open label, phase I (3 + 3 design), multi-centre study evaluating panobinostat in pediatric patients with refractory solid tumors.

Keywords:

Refractory
Oncology
Pharmacology
CNS TUMORS
Panobinostat
Medicine
Internal medicine
Gastroenterology
Cmax
Neutropenia
Anemia
Adverse effect
Pharmacokinetics
Tolerability

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