Protecting the Mitochondria Against Ischemia Reperfusion: A Gassy Solution?

Organ transplantationsuccess has seen great improvements in past decades due to progresses in immune-suppressive regiments. However, lack of long-term graft outcome improvement, added to increased marginal donors use, has recently shifted the focus towards the peri-transplant period and particularly ischemia reperfusion injury(IRI). The recent acknowledgment of the link between IRI and outcome, short or long term, has rekindled interest in the study of the physiopathology associated with organ preservation and the methods to optimize it. This article is protected by copyright. All rights reserved.