Validating Rheumatoid Arthritis Remission Using the Patients’ Perspective: Results from a Special Interest Group at OMERACT 2016
2017
Objective. The Outcome Measures in Rheumatology (OMERACT) working group on the patients’ perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of
measurement instrumentsfor pain, fatigue, and independence in remission in RA were presented, and future directions were explored. Methods. A
special interest groupwas organized, in which the current data on the patients’ perspective on remission were presented. The ongoing study that aimed to validate
measurement instrumentsfor pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on
construct validityand discriminative capacity were evaluated cross-sectionally. Results. At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (
construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding
patient-reported outcomes(PRO), or by substituting the patient’s global assessment with 1 or more PRO. Conclusion. More evidence on measuring patients’ perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.
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