Catalytic Asymmetric Allylation of Aldehydes with BINOL-Ti(IV) Complex Accelerated by i-PrSSiMe3.

Abstract Practical and efficient catalytic asymmetric allylation reaction of achiral aldehydes with allyltri-n-butylstannane in the presence of chiral Lewis acid catalyst has been achieved by the use of accelerator, i-PrSSiMe3. This system exhibited not only dramatically accelerating reactivity but also significantly increasing catalytic ability.