Predictors of venous thromboembolism in patients with glioblastoma multiforme.

e13022 Background: Patients with glioblastoma multiforme (GBM) have a high risk of developing venous thromboembolism (VTE). We conducted a single centerretrospective review to study the impact of various clinical factors on the risk of developing VTE. Methods: A retrospective chart review was conducted to identify patients diagnosed with GBM between 2001-2011. A total of 1002 patients were identified. Cases (n = 162) were defined as patients who developed VTE after diagnosis of GBM. Controls (n = 840) were patients without a diagnosis of VTE after diagnosis of GBM. Data was reviewed for age, sex, race, length of stay after brain surgery/biopsy, total number of hospital admissions, Karnofsky Performance Status(KPS), bevacizumab use and bleeding episodes. Results: The median age for development of a VTE was 61.8 ± 11.4 years. Mean time to development of VTE after GBM surgery was 78.3 days. In the VTE group, 78% had a KPS of ≤ 70, whereas only 18% of the controls had a KPS ≤ 70. Average inpatient stay afte...