Reduced expression of L-selectin in T-cells correlates with relative lymphocyte increase in patients with RRMS treated with natalizumab - functional implication towards PML risk

Marina Boziki,Theodoros Karapanayotides,Georgios C. Papadopoulos,Roza Lagoudaki,Pamela Melo,Christos Bakirtzis,Ioannis Nikolaidis,Evdoxia Gounari,Vasiliki Tsavdaridou,Lemonia Skoura,Theodora Afrantou,Theano Tatsi,Eleni Grigoriadou,Eleni Polyzoidou,Nikolaos Mandoras,Virginia Giantzi,Anna Kalogera-Fountzila,Panagiotis Ioannidis,Dimitrios Parissis,Sygkliti-Henrietta Pelidou,Sofia Zoidou,Nikolaos Grigoriadis

Reduced expression of L-selectin in T-cells correlates with relative lymphocyte increase in patients with RRMS treated with natalizumab - functional implication towards PML risk

2020

ABSTRACTObjectives: Natalizumab (NTZ), a treatment indicated for patients with highly active Relapsing – Remitting Multiple Sclerosis (RRMS), is known to induce increased relative frequency of lymp...

Keywords:

Diabetes mellitus
Multiple sclerosis
Medicine
Lymphocyte
Anesthesia
functional implication
Natalizumab
Progressive multifocal leukoencephalopathy
Immunology
L-selectin
in patient

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