Mesh covered stent in ST-segment elevation myocardial infarction

Aims: The MGuard stent (bare metal stent wrapped externally with a polymer mesh sleeve) is designed to p revent distal embolisation by reducing thrombus and plaque fragments released during and post percutaneous coronary intervention (PCI). The aim of this study was to confirm the clinical feasibility, safety and performance of the MGuard stent during primary PCI for ST-segment elevation myocardial infarction (STEMI). Methods and results: The present study was a multicentre, prospective, single arm study in which 60 patients with STEMI 70%) ST-segment resolution 60 minutes after PCI in 61.4% of patients. In 5.0% of cases distal embolisation occurred. The total major adverse cardiac events rate during the 6-month follow-up was 1.7%. Conclusions: Based on this experience, the MGuard stent implantation in STEMI patients is safe and highly effective. A larger randomised trial is warranted to confirm the clinical endpoints.