Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms.

Samir Mehndiratta,Mei Chuan Chen,Yuh Hsuan Chao,Cheng Hsin Lee,Jing Ping Liou,Mei-Jung Lai,Hsueh Yun Lee

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms.

2021

Samir Mehndiratta
Mei Chuan Chen
Yuh Hsuan Chao
Cheng Hsin Lee
Jing Ping Liou
Mei-Jung Lai
Hsueh Yun Lee

A series of 3-subsituted quinolinehydroxamic acids has been synthesised and evaluated for their effect on human lung cancer cell line (A549), human colorectal cancer cell line (HCT116) and HDAC iso...

Keywords:

Hydroxamic acid
Quinoline
Cell culture
Acrylamide
Chemistry
Gene isoform
Colorectal cancer
Cancer research
Lung cancer
Histone deacetylase

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