314 Transcatheter closure of large patent ductus arteriosus using the Amplatzer duct occluder in infants under 2 years of age

Introduction and objectives Percutaneous closure of patent ductus arteriosus(PDA) is a well-established technique. We evaluated the usefulness of the Amplatzer duct occluder (ADO) for the percutaneous closure of large patent ductus arteriosusin 16 children less than 2 years of age. Methods The patient's mean age was 15, 5 months (from 6 to 24 months) and their mean weight was 8, 6 (4–13, 5) kg. In addition, 2 patients were under 5 Kg. mean symptoms were recurrent pulmonary infections (7 patients), dyspnea (5 patients) and 2 of them had patent cardiac failure. All completed follow-up (3 months – 6 years). Results The mean PDA diameter was 4.4, 8(2–6) mm. dilated left ventricular was noticed in all cases and pulmonary hypertension within 7 cases. The device was implanted successfully in all the patients. Sizes of the device were 10/8 in one case, 8/6 in 9 cases, 6/4 in 6 cases. Aortographyshowed initial total occlusion in 65.8% of patients. At 3-month follow-up, total occlusion was observed in 100% of patients. No deaths or significant complications were associated with the procedure during the study period. One patient develop hemopericardiumwith tamponade witchtreated successfully by pericardiocentesis. Conclusions In children under 2 years of age, percutaneous closure of large patent ductus arteriosususing an Amplatzer occluder was a safe and effective procedure.