Construction of Strontium Phosphate/Graphitic-Carbon Nitride: A Flexible and Disposable Strip for Acetaminophen Detection

Abstract A facile technique has been used to synthesize the strontium phosphate interlinked with graphitic carbon nitride nanosheets (SrP/g-CN) nanocomposite for highly selective detection of acetaminophen (AP). The formation of SrP/g-CN NSs nanocomposite is evidenced by several spectroscopic and analytical methods. It was demonstrated that the SrP/g-CN NSs modified screen-printed carbon electrode (SPCE) exhibits excellent catalytic performance with low peak potential towards AP detection than those of pristine SrP–, g-CN NSs–, and bare– SPCEs. The outstanding electrochemical performance can be attributed to the robust synergistic effect between SrP and g-CN NSs. Likewise, g-CN NSs possess a porous multilayer network, which provides a large surface area, fast charge transferability, electrical conductivity, and numerous active sites. Under the optimal conditions, the fabricated sensor could detect AP with a linear relationship range from 0.01 to 370 µM, and the detection limit is calculated to be as low as 2.0 nM. Besides, the SrP/g-CN NSs/SPCE shows good sensitivity, excellent selectivity, stability, and reproducibility. The proposed sensor is successfully used to determine AP in biological and water samples with satisfactory results. This work provides an auspicious paradigm for the design and development of a metal-based modified SPCE with efficiency in the electrocatalytic field.