The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
2014
The E3 ligase Cbl-b acts on TAM
tyrosine kinasereceptors and has a critical role in the regulation of natural killer (NK) cell rejection of metastatic tumours; a
small moleculeTAM kinase inhibitor is shown to enhance the anti-metastatic NK cell activity.
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