Comparative analysis of X-ray Crystallographic Behavior of some Pyrazolone Derivatives: Comparative analysis of X-ray Crystallographic Behavior of some Pyrazolone Derivatives

X-ray structural investigations have been compared for the three Pyrazolone derivatives,        (Z)-3-Methyl-1-phenyl-4-[(p-tolyl)(p-tolylamino)methylidene]-1H-pyrazol-5(4H)-one (I), (Z)-3-Methyl-4-[1-(4-methylanilino)-propylidene]-1-phenyl-1H-pyrazol-5(4H)-one (II) and (Z)-3-Methyl-4-((naphth-1-ylamino)methylidene)-1-phenyl-1H-pyrazol-5(4H)-one (III) respectively. The compounds (I), (II) and (III) were crystallizes in the monoclinic, triclinic and orthorhombic crystal system with space group P21/n, P-1 and P212121 respectively. The pyrazole ring in all the three compounds is planar. In the crystal structure of compound (I), (II) and (III), the molecules are linked by an elaborate system of N-H···O hydrogen bonds. The crystal structures of all the three molecules were solved by direct method using single crystal X-ray diffraction data collected at room temperature and refined by full-matrix least-squares procedures. The X-ray crystallographic properties of these synthesized compounds of biological relevance are compared herein.