Early Effect of Single-dose Sitagliptin Administration on Gastric Emptying: Crossover Study Using the 13 C Breath Test
2013
Background/Aims
The gastrointestinal motility effects of endogenous incretin hormones enhanced by dipeptidyl peptidase-IV (DPP-IV) inhibitors have not yet been sufficiently investigated. The aim of this study was to determine whether single pre-prandial sitagliptin, the DPP-IV inhibitor, administration might have an effect on the rate of liquid gastric emptying using the 13C-acetic acid breath test.
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