Gremlin Is a Downstream Profibrotic Mediator of Transforming Growth Factor-Beta in Cultured Renal Cells

Raquel Rodrigues-Díez,Carolina Lavoz,Gisselle Carvajal,Sandra Rayego-Mateos,Raúl Rodrigues Díez,Alberto Ortiz,Jesús Egido,Sergio Mezzano,Marta Ruiz-Ortega

Gremlin Is a Downstream Profibrotic Mediator of Transforming Growth Factor-Beta in Cultured Renal Cells

2012

Raquel Rodrigues-Díez
Carolina Lavoz
Gisselle Carvajal
Sandra Rayego-Mateos
Raúl Rodrigues Díez
Alberto Ortiz
Jesús Egido
Sergio Mezzano
Marta Ruiz-Ortega

Background/Aims: Chronic kidney disease is characterized by accumulation of extracellular matrix in the tubulointerstitial area. Fibroblasts are the main matrix-p

Keywords:

Endocrinology
Internal medicine
Epithelial–mesenchymal transition
Kidney disease
Extracellular matrix
Transforming growth factor, beta 3
Transforming growth factor beta
Mediator
Biology
Diabetes mellitus
renal fibrosis

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