Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment

Jessica González-Sánchez,Agustin Sanchez-Temprano,Tania Cid-Díaz,Regina Pabst‐Fernández,Carlos S. Mosteiro,Rosalía Gallego,Rubén Nogueiras,Xesús Casabiell,Gillian Butler-Browne,Vincent Mouly,José Luis Relova,Yolanda Pazos,Jesus P. Camiña

Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment

2018

Jessica González-Sánchez
Agustin Sanchez-Temprano
Tania Cid-Díaz
Regina Pabst‐Fernández
Carlos S. Mosteiro
Rosalía Gallego
Rubén Nogueiras
Xesús Casabiell
Gillian Butler-Browne
Vincent Mouly
José Luis Relova
Yolanda Pazos
Jesus P. Camiña

Background This study was performed to test the therapeutic potential of obestatin, an autocrine anabolic factor regulating skeletal muscle repair, to ameliorate the Duchenne muscular dystrophy (DMD) phenotype.

Keywords:

Duchenne muscular dystrophy
Diabetes mellitus
Endocrinology
Skeletal muscle
Obestatin
Internal medicine
Medicine
Sarcolemma
Myogenesis
Myocyte
Muscle atrophy
Utrophin

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