Steroid-resistant protein-losing gastroenteropathy complicated with Sjögren’s syndrome successfully treated with mizoribine

AbstractA 64-year-old woman with leg edemawas diagnosed with protein-losing gastroenteropathy and Sjogren’s syndrome. Central venous nutrition led to infection of her catheter, ascites, and deep veinthrombosis. Following successful treatment of these conditions with antibiotics and anticoagulants, she was treated unsuccessfully with prednisoloneand steroid pulse therapy. Mizoribineadd-on markedly reduced edemaand normalized serum albumin. This is the first report of a steroid-resistant protein-losing gastroenteropathy patient with Sjogren’s syndrome successfully treated with mizoribine.