Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells
2019
Anagrelide is widely used as a therapeutic agent for patients with essential thrombocythemia (ET).[1][1] It was initially developed as an antiplatelet aggregation drug by inhibition of phosphodiesterase III,[2][2] and its primary effect at therapeutic concentrations is on the post-mitotic phase of
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