Development, evaluation and use of COVID-19 vaccines in older adults: Preliminary principles for the pandemic and beyond.

The COVID-19 pandemic brought development, evaluation and use of vaccines for older adults into the spotlight. Here, we reflect on the gaps that were highlighted and strategies to fill them, during the pandemic and beyond. This commentary draws on principles we compiled through the geriatric pharmacology subcommittee of the clinical division of the International Union of Basic and Clinical Pharmacology (IUPHAR), to guide the regulation and use of the COVID-19 vaccines for older adults.These are based on principles for evaluation and use of other therapeutics in older people.