Exercise-related anaphylaxis with food allergy to cross-reactive LTPs

2013 
Background In food dependent exercise-induced anaphylaxis, a food challenge followed by an exercise test, being the gold standard for diagnosis, might not be feasible under certain circumstances. Therefore, in vitro diagnostic tests can be helpful to clarify severe forms of exercise-related hypersensitivity syndromes. We report two patients with food allergy to non-specific LTPs presenting as exerciserelated anaphylaxis after food intake. Our aim was to identify IgE cross-reactivities using an in-vitro depletion assay with the suspected native allergens, and an allergen microarray.
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