Development and validation of Cognitive Training Intervention for Alzheimer’s disease (CTI-AD): A picture-based interventional program

IntroductionAlzheimer’s disease is a gradual and progressive disorder which cripplesthe person’s functionality due to cognitive decline. Many clinicopathological and pharmacological therapy has the potential to slow down the progression of the disease but has limited efficacy. One complimentary approach that has emerged is cognitive traininginterventions which have shown synergistic effect with the drug therapy. Nevertheless, many cognitive interventions lack on specificities of the intervention due to which its efficacy gets scrutinized.ObjectiveTo describe the foundation, content, and development of Cognitive TrainingIntervention for Alzheimer’s disease (CTI-AD) along with the treatment feasibility based on a pilot study.Materials and methodsA culture-specific picture-based eight weeks cognitive trainingmanual was developed based on extensive review and focused group discussions. It was standardized on 63 older participants (48 healthy controls (HC); 15 early Alzheimer’s disease cases).ResultsAll th...