Association between SLCO1B1 rs4149056 and tegafur-uracil-induced hepatic dysfunction in breast cancer

Hidenori Kamio,Takako Kamio,K. Shikama,M. Nogami,Eiichiro Noguchi,Tetsuya Ohchi,Toshitaka Uchiyama,Hitoshi Kanno,Kayoko Saito,Takahiro Okamoto

Association between SLCO1B1 rs4149056 and tegafur-uracil-induced hepatic dysfunction in breast cancer

2017

Hidenori Kamio
Takako Kamio
K. Shikama
M. Nogami
Eiichiro Noguchi
Tetsuya Ohchi
Toshitaka Uchiyama
Hitoshi Kanno
Kayoko Saito
Takahiro Okamoto

Aim: The aim of this study was to identify pharmacogenomic biomarkers to predict tegafur–uracil (UFT)-induced liver dysfunction. Patients & methods: A total of 68 patients, who were administered UF...

Keywords:

Cancer
Breast cancer
SLCO1B1
Hepatic dysfunction
Medicine
Tegafur/uracil
Oncology
Internal medicine

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