Metformin in obese children and adolescents: the MOCA trial

Royal Manchester Children’s Hospital (D.K., R.A., F.I., A.M., L.T., P.C., C.H.), Manchester M13 9WL, United Kingdom; Birmingham Children’s Hospital (T.B.), Birmingham, B4 6NH, United Kingdom; Sheffield Children’s Hospital (P.D., J.W., N.W.), Western Bank, Sheffield S10 2TH, United Kingdom; The University of Sheffield (P.D., J.W., N.W.), Western Bank, Sheffield S10 2TN, United Kingdom; The James Cook University Hospital (M.K.), Middlesbrough, Cleveland TS4 3BW, United Kingdom; Hull Royal Infirmary (V.M.), Hull, East Yorkshire HU3 2JZ, United Kingdom; University Hospital Coventry and Warwickshire National Health Service Trust (K.M., H.S.), Coventry CV2 2DX, United Kingdom; Centre for Biostatistics (A.V.), University of Manchester, Manchester Academic Health Science Centre, Salford Royal National Health Service Foundation Trust, Salford M6 8HD, United Kingdom; and Manchester Academic Health Sciences Centre (P.C.), University of Manchester, Manchester M13 9PL, United Kingdom