Histological features of primary tumors after induction or high-dose chemotherapy in high-risk neuroblastoma

Purpose In the recent years in Japan, an increasing number of patients with neuroblastoma(NB) are being treated by the “delayed local treatment (DL)” policy, undergoing surgery after the completion of high-dose chemotherapy with hematopoietic stem cellrescue (HDC). We reviewed the histopathological findings of second-look operations, including those of patients treated with DL.