An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species
2018
Herein, we developed a strategy to attack the
cancer celldefense system against
reactive oxygen speciesto improve
photodynamic therapyefficacy with a Ce6@MSN@MTH1 siRNA nanosystem, which was demonstrated to improve cellular sensitivity to
reactive oxygen speciesthrough suppressing MTH1 protein in
cancer cells.
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