Interleukin 1 blockade with canacinumab for hyperimmunoglobulin D and periodic fever syndrome.

Hyperimmunoglobulinemia D and periodic fever syndrome(HIDS; MIM# 260920) is a rare autosomalrecessive autoinflammatory condition caused by mutations in the MVK gene, which encodes for mevalonate kinase. There is no standard treatmentfor HIDS.