Hidradenitis Suppurativa in Down Syndrome: A Case Series

Background/Objectives Many dermatologicand systemic diseases have been reported in association with hidradenitis suppurativa, but its association with Down syndromeis rarely mentioned in the literature. The objective of the current study was to assess the frequency of hidradenitis suppurativain patients with Down syndromewho visited our clinic over 4 years. Methods We recorded the presenting complaints and dermatologicproblems of patients with Down syndromewho visited our clinic from January 2011 to December 2014. Medical photographs were taken. Patients with hidradenitis suppurativawere assessed according to severity and treated with topical and systemic medications. Results Twenty-nine new patients with Down syndromevisited our clinic during this period. Eleven had hidradenitis suppurativa. Disease severity included Hurley stages I and II. Conclusion The presence of hidradenitis suppurativain 38% of patients with Down syndromeis far higher than would be expected by chance alone.