Validation and identification of reference genes in Chinese hamster ovary cells for Fc-fusion protein production.

Xiaonan Ma,Ling Zhang,Luming Zhang,Chenglong Wang,Xiaorui Guo,Yu Yang,Lin Wang,Xiangru Li,Ningning Ma

Validation and identification of reference genes in Chinese hamster ovary cells for Fc-fusion protein production.

2020

Xiaonan Ma
Ling Zhang
Luming Zhang
Chenglong Wang
Xiaorui Guo
Yu Yang
Lin Wang
Xiangru Li
Ningning Ma

Chinese hamster ovary cells are the predominant cell lines used for bio-therapeutic production. Real-time quantitative PCR (RT-qPCR) and transcriptomics are powerful tools to understand and optimiz...

Keywords:

Reference genes
Real-time polymerase chain reaction
Chinese hamster ovary cell
Molecular biology
Transcriptome
RNA-Seq
Biology
Fusion protein
Cell culture
Internal medicine
Endocrinology
Protein biosynthesis
fc fusion

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