Pediatric Miller Fisher Syndrome Complicating an Epstein–Barr Virus Infection

Abstract Background Miller Fisher syndrome, a variant of Guillain–Barre syndrome, is an acute inflammatory demyelinating polyradiculoneuropathythat may occur weeks after a bacterial or viral infection. Campylobacter jejuniand Haemophilus influenzaeare frequently reported etiological agents. Patient Description We describe a boy with Miller Fisher syndromefollowing Epstein-002DBarr virus primary infectious mononucleosis. He presented with bilateral dysfunction of several cranial nervesand hyporeflexiaof the limbs but without ataxia. Miller Fisher syndromewas confirmed by the presence of anti-GQ1b antibodies in a blood sample. Epstein–Barr viruswas identified by polymerase chain reaction and serology. Conclusion Epstein-Barr virusshould be considered as a MillerFisher syndrome's causative agent. The physiopathology of this condition may involve cross-reactive T-cells against Epstein-Barr virusantigens and gangliosides.