Complete remission with intraperitoneal cisplatin followed by prolonged oral etoposide in a stage IIIc primary leiomyosarcoma of the fallopian tube patient
2010
Leiomyosarcoma(LMS) of the
fallopian tubeis exceedingly uncommon. So far as we investigated, only eighteen cases of LMS of the
fallopian tubehave been reported. Here we report a nineteenth case which was International Federation of Gynecology and Obstetrics stage IIIc LMS of the
fallopian tubesuccessfully treated with intraperitoneal cisplatin followed by prolonged oral
etoposide. A 70-year-old female was introduced to our institute due to intrapelvic tumor and ascites. Because of elevated serum lactate dehydrogenase and CA125 as well as the findings of pelvic magnetic resonance imaging and computerized tomography, the patient was suspected to have ovarian cancer. In laparotomy, the large
pelvic tumorwas seemed to originate from the right
fallopian tube. Pathologically, the patient was diagnosed as stage IIIc
fallopian tubeLMS. At the end of the operation, cisplatin was given intraperitoneally followed by prolonged oral
etoposide. Although a lot of dissemination was noted throughout the
peritoneal cavity, the patient is alive without any evidence of recurrence for more than 6 years since the initial operation. In this uncommon entity, a cisplatin- and
etoposide-based regimen could be considered.
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